At the 2013 Opening Session of the American Society of Anesthesiologists meeting, Charles Denham, M.D. presents “Chasing Zero: The Innovators Arena,” challenging Anesthesiologists to face the challenges before them and lead innovation just as they have done in the past. The presentation is divided into several parts addressing the 4T’s of Leadership – Truth, Trust, Teamwork, and Training. The presentation is enhanced with multimedia including an extensive interview with actor and patient safety champion, Dennis Quaid.